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Surveillance of blood donors detects an exceptional Parvovirus B19 outbreak in Switzerland in 2023/2024.

Year: 2025

Type: article

Abstract: BACKGROUND: Human Parvovirus B19 is a common human pathogen that causes fifth disease that can be severe for immunocompromised people and unborn children. Blood donations are routinely screened for the presence of Parvovirus B19 DNA to release plasma for the fractionation industry. MATERIALS AND METHODS: IU/mL are removed from the blood supply and the viral genotype, viral titers, and serological status were determined. RESULTS: IU/mL. Serological data show an inverse correlation between viral titers and presence of protective IgG antibodies. DISCUSSION: Similar to the situation in other European countries, Switzerland was struck with an unprecedented Parvovirus B19 outbreak in 2023/2024. The outbreak follows a two-year stretch with no positive Parvovirus B19 cases. It is likely that the measures implemented in 2020 to confine the spread of SARS-CoV-2 had a strong impact on other infectious diseases like Parvovirus B19.

Source: PubMed

DOI: 10.48620/90400