Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVES: to determine the prevalence and identify the factors associated with bacterial infection in cirrhotic patients in Togo. METHODS: This was a descriptive and analytical cross-sectional study, with retrospective data collection, conducted in the hepato-gastroenterology department of the Campus University Hospital during three years. All patients hospitalized in the department during this period and diagnosed with cirrhosis were included in the study. RESULTS: During the study period, 270 patients were hospitalized for cirrhosis including 63 cases of bacterial infection, a prevalence of 23.3%. Bacterial infections were represented by spontaneous infection of ascites fluid (15.9%) followed by urinary tract infection (4%). The median length of hospital stay was 10 days Thirty-six of the patients with infection died in hospital, corresponding to a mortality rate of 57.1%. Factors associated with bacterial infection were ascites (P=0.017; OR=4.56), hepatic encephalopathy (P=0.02; OR=4.32), a prothrombin level below 25% (P=0.002; OR=9.67) and a high MELD score (P=0.03; OR=0.93). CONCLUSION: Bacterial infection occurs in advanced cirrhosis and is associated with a poor prognosis. BACKGROUND: • Bacterial infections are a frequent complication of cirrhosis and were associated with ascites, hepatic encephalopathy and a high MELD score. BACKGROUND: • The most frequent type of infection in this study was spontaneous bacterial peritonitis followed by urinary tract infection.
Source: Arquivos de Gastroenterologia
Institution: University of Lomé
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412528031