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Case Report of a Non-Small-Cell Lung Cancer Patient with Cytotoxic Chemotherapy-Induced Neutropenia Treated with Korean Medicine

Year: 2025

Type: article

Abstract: Objectives: To report a case of non-small-cell lung cancer (NSCLC) with chemotherapy-induced neutropenia that improved following Korean medicine treatment.Methods: After developing neutropenia following the first cycle of cytotoxic chemotherapy, a patient with NSCLC received Korean medicine treatment including herbal medicine (Ikgibohyeol-tang) and acupuncture. To evaluate the therapeutic effect, changes in ANC levels and G-CSF dosage were assessed along with tumor response via computed tomography and magnetic resonance imaging and symptom changes using the FACT-L questionnaire.Results: After treatment, the patient showed improvement in the severity grade of neutropenia and lower G-CSF usage. The tumor size reduced, and the FACT-L score improved slightly.Conclusion: This case suggests that Korean medicine treatment may serve as a supportive therapy for managing chemotherapy-induced neutropenia in cancer patients.

Source: The Journal of Internal Korean Medicine

DOI: 10.22246/jikm.2025.46.3.521

Authors: Min-jun Lee, Dae-jun Choi, Su-hyun Chin, Jae-hwan Lew

Institution: Kyung Hee University

Language: English

Topic: Medical Research and Treatments

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412538280