Work

Synthesis of 1,2,3,4-tetrahydroacridine based 1,2,3-triazole derivatives and their biological evaluation as dual cholinesterase and α-glucosidase inhibitors

Year: 2025

Type: article

Abstract: A series of new 1,2,3-triazole-linked tacrine derivatives were synthesized using click reaction of C4-functionalized 9-azido-1,2,3,4-tetrahydroacridines and various phenyl acetylenes including tacrine-based terminal alkynes.

Source: New Journal of Chemistry

DOI: 10.1039/d5nj02221e

Authors: Thangellapally Shirisha, Subir Majhi, Kalivarathan Divakar, Dhurke Kashinath

Institution: National Institute of Technology Warangal

Language: English

Topic: Click Chemistry and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Department of Science and Technology, Ministry of Science and Technology, India, Ministry of Education, India, Science and Engineering Research Board

Awards: G2200841858, G2400301908, G26222736, G4398328989, G6459246554

OpenAlex ID: W4412548288

FWCI: 0.894

Cites: 32

Cited by: 3

Related to: 10