Profiling and quantification of milk oligosaccharides during early- and late- lactation stages in crossbred (Nili-Ravi × Murrah × local) buffaloes from Guangxi, China
Year: 2025
Type: article
Abstract: Human milk oligosaccharides offer unique benefits for infant growth and development. Buffalo milk, characterized by a mild flavor and high nutritional value, has attracted considerable interest. To characterize the oligosaccharide profile and composition of buffalo milk, we conducted qualitative and quantitative analysis of milk oligosaccharides at the early- and late-lactation stages of crossbred (Nili-Ravi × Murrah × local) buffaloes from Guangxi, China. The results revealed a total of 97 oligosaccharides including 17 novel oligosaccharides, with concentrations of 416.6 ± 25.86 and 368.3 ± 10.29 mg/L in milk from early- and late-lactation stages, respectively. The most abundant oligosaccharides were 3’-sialyllactose (3’-SL), difucosyllactose (DFL), 6’-sialyllactose (6’-SL), and a newly discovered compound, 2142. The oligosaccharides in crossbred (Nili-Ravi × Murrah × local) buffaloes demonstrated greater diversity than those found in the milk of other dairy animals, highlighting its potential as a high-quality nutritional resource for adults and infants.
Source: Animal Nutriomics
Authors: Junyan Han, Haijing Wu, Yiqiang Li, Deshuang Wei, Xiaofeng Xu, Huien Zhang, Shangjun Yin, Jiakun Wang, Bo Lin, Qian Wang
Institutions: Zhejiang Wanli University, Zhejiang University, Guangxi University
Language: English
Topic: Infant Nutrition and Health
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,000
OpenAlex ID: W4412588276