Fabrication and characterization of a multifunctional alginate–gelatin–fibrinogen hydrogel for potential muscle tissue reconfiguration in vitro
Year: 2025
Type: article
Abstract: enzymatic and/or ionic methods resulted in flexible tunability of the modulus and porosity of the material. Experimental findings using C2C12 myoblast cells grown on the alginate-gelatin-fibrinogen hydrogel surface demonstrate that this biomaterial facilitates 3D bioprinting of anatomically complex muscle tissue constructs and biohybrid robotic systems. Overall, this study provides a novel strategy for the application in muscle tissue construction, repair, and bio-robotics through designing alginate-gelatin-fibrinogen composite hydrogels.
Source: Journal of Materials Chemistry B
DOI: 10.1039/d5tb00912j
Authors: Zening Lin, Yang Hong, Tao Jiang, Yun Yang, Yuan Gao, Hang Xie, Zirong Luo
Institution: National University of Defense Technology
Language: English
Subfield: Molecular Medicine
Domain: Life Sciences
Open Access status: hybrid
Award: G6350044698
OpenAlex ID: W4412596284