Work

A dual-targeting photosensitizer for simultaneous mitochondrial and lysosomal disruption in cancer and antibacterial photodynamic therapy

Year: 2025

Type: article

Abstract: MCQ-1 is a dual-functional type I photosensitizer, capable of targeting both mitochondria and lysosomes in cancer cells, while also exhibiting selective antibacterial activity against Gram-positive bacteria, including MRSA.

Source: Journal of Materials Chemistry B

DOI: 10.1039/d5tb01345c

Authors: Chaewoon Cho, K. M. K. Swamy, Bingqing Sun, Gyoungmi Kim, Lei Liu, Won Jun Jang, Juyoung Yoon

Institutions: Ewha Womans University, Anhui University of Science and Technology, Anhui Science and Technology University

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Research Foundation, Ewha Womans University, National Research Foundation of Korea, Anhui University of Science and Technology, Ministry of Science and ICT, South Korea

Awards: G612905748, G6783236265, G7545057034, G7572541277, G8980125925

OpenAlex ID: W4412609824

FWCI: 4.253

Cites: 37

Cited by: 7

Related to: 10