Work

Utilisation of CO 2 in the simultaneous installation of the C–C and CC bonds of α,β-unsaturated carboxylic acids

Year: 2025

Type: article

Abstract: Exploiting the ability of phosphonium ylides both to activate CO 2 and to form new CC bonds, a Wittig CO 2 utilisation strategy has enabled a very direct and regioselective means of synthesising α,β-unsaturated carboxylic acids.

Source: Organic Chemistry Frontiers

DOI: 10.1039/d5qo00770d

Authors: Amy Lowry, Rachel E. Lynch, Gerard P. McGlacken, Peter A. Byrne

Institutions: University College Cork, University College Dublin, Taighde Éireann - Research Ireland, Synthesis and Solid State Pharmaceutical Centre

Language: English

Topic: Phosphorus compounds and reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Climate action

Open Access status: hybrid

Funders: Synthesis and Solid State Pharmaceutical Centre, Science Foundation Ireland, University College Dublin, University College Cork, Irish Research Council, Research Ireland

Awards: G2008096578, G2905070923, G379591829, G4816631642, G5098725405, SSPC_Phase 2, Process Flow Spectroscopy (ProSpect); Advanced Reaction Understanding using Flow Nuclear Magnetic Resonance (NMR) and Infrared (IR) Spectroscopies, with On-Line Ultra-Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS), G8268664507

OpenAlex ID: W4412611110

FWCI: 0.298

Cites: 87

Cited by: 1

Related to: 10