Work

The irreplaceable art of brachytherapy: A technical note on interstitial high-dose-rate interventional radiotherapy (brachytherapy) in eyelid tumors

Year: 2025

Type: article

Abstract: Purpose: Eyelid tumors are uncommon malignancies, where 75% of cases are cutaneous basal cell carcinoma (BCC), and sebaceous cell carcinoma, squamous, adenocarcinoma from meibomian glands are diagnosed in 25%. Post-excision adjuvant radiotherapy (ART) is indicated in high-grade tumors with positive margins and lymphovascular space or perineural invasion. The ideal technique for delivering ART for eyelid tumors is interstitial brachytherapy (ISBT). However, its use is limited by steep learning curve. Here, we described the stepwise procedure of ISBT performed in eyelid tumors with reported outcomes. Material and methods: dosimetry was performed using metal-oxide-semiconductor field-effect transistor (MOSFET). Results: (TPS) was 1.28 Gy/fraction, while the mean dose recorded by MOSFET was 0.7 Gy/fraction. No conjunctival acute toxicities were observed. Grade 1 skin reaction (hyperpigmentation) was noted, with no local recurrences at 1 year median follow-up. Conclusions: ART delivered by ISBT in eyelid tumors is a simple and efficient brachytherapy procedure, providing excellent cosmesis and local control.

Source: Journal of Contemporary Brachytherapy

DOI: 10.5114/jcb.2025.152542

Authors: Tanvir Pasha, Nikhila Radhakrishna, Sushma Poojar, Rashmi Shivananjappa, Bharathi Krishnamoorthy, Naveen Thimmaiah

Institution: Kidwai Memorial Institute of Oncology

Language: English

Topic: Ocular Oncology and Treatments

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $269