Cardiovascular Rehabilitation in a Clinical Case of a Patient with Marfan Syndrome
Year: 2025
Type: article
Study design: Case Report
Abstract: Marfan syndrome is a genetic connective tissue disorder with autosomal dominant inheritance, caused by a mutation in the gene encoding for fibrillin 1 (FBN1), located on chromosome 15. This mutation causes excessive secretion of the transforming growth factor beta (TGF-beta), causing changes in connective tissue throughout the body - multisystemic disease (especially affecting the eye, cardiovascular and musculoskeletal level). We hereby present the case of a 24-year-old male patient, diagnosed with Marfan syndrome, that was admitted in the Cardiovascular Rehabilitation Clinic of the Clinical Rehabilitation Hospital from Iași, Romania, for cardiovascular recovery after a surgical intervention for aortic dissection, performed through the Bentall procedure.
Source: Internal Medicine
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4412623130