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Author response: Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells

Year: 2025

Type: peer-review

Abstract: Analyses of zebrafish meioc mutants revealed that spermatogonial stem cells with low rRNA transcription caused by nucleolar Piwil1 require Meioc to keep Piwil1 in cytoplasm for the upregulation of rRNA transcription necessary for differentiation.

Source: eLife

DOI: 10.7554/elife.104295.3.sa4

Authors: Toshihiro Kawasaki, Toshiya Nishimura, Naoki Tani, Carina Ramos, Emil Karaulanov, Minori Shinya, Kenji Saito, Emily Taylor, René F Ketting, Kei-ichiro Ishiguro, Minoru Tanaka, Kellee R Siegfried, Noriyoshi Sakai

Institutions: National Institute of Genetics, The Graduate University for Advanced Studies, SOKENDAI, Nagoya University, Kumamoto University, University of Massachusetts Boston, Institute of Molecular Biology, Institute of Molecular Biology, Institute of Molecular Embryology and Genetics, Kumamoto University

Language: English

Topic: Sperm and Testicular Function

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $2,500

OpenAlex ID: W4412630754

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