Work

Transforming docetaxel delivery: lung-targeted polyphosphazene nanoparticles with enhanced safety profile

Year: 2025

Type: article

Abstract: metabolic profiling revealed a distinct biodegradation and clearance mechanism, with minimal generation of inactive or toxic metabolites. These results highlight the potential of PTX as a safe and effective drug delivery platform that combines enhanced therapeutic performance with reduced systemic burden, supporting its future clinical translation in cancer chemotherapy.

Source: Nanoscale

DOI: 10.1039/d5nr02201k

Authors: Sanoj Rejinold N, Geun-Woo Jin, Ji Eun Oh, Hye Hyun Yoo, Jin-Ho Choy

Institutions: Dankook University, Hanyang University, National Academy of Sciences

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea