Year: 2025
Type: review
Abstract: Pulsatile signal detection plays an important role in monitoring various physiological parameters, primarily heart rate and blood oxygen saturation. Their applications range from clinical settings to personal health and wellness monitoring. PPG (photoplethysmography) can provide non-invasive optical measurements to detect blood volume changes in peripheral tissues. Yet, it suffers from low spatial resolution to precisely detect the pulsatile signal originating over 2 mm in human tissue. Ultrasound (US) provides a deep detectable range compared to the pure optical method. However, its low contrast to red blood cells and cluster artifacts makes it only detect the indirect pulsation from the surrounding tissue of blood vessels. Recent advances in PA imaging show its capability to precisely measure pulsatile signals originating from blood vessels in deep regions (over 10 mm) and its potential to accurately record blood oxygen saturation with high spatial and temporal resolution. This review article summarizes studies on photoacoustic (PA) pulsatile signal monitoring, highlights the technical advances, and compares it against optical and ultrasonic approaches.
Source: Biosensors
DOI: 10.3390/bios15090591
Authors: Wenhan Zheng, Chuqin Huang, Jun Xia
Institution: University at Buffalo, State University of New York
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,654
OpenAlex ID: W4414142664