High burden of chronic kidney disease of unknown cause among patients receiving renal replacement therapy in Northeast Nigeria: A cross-sectional survey of haemodialysis units
Year: 2024
Type: preprint
Study design: Observational Study
Abstract: Background: Chronic kidney disease (CKD) is emerging as a significant public health concern in northeastern Nigeria, particularly in states such as Yobe and Borno. Despite its increasing impact, there is a lack of data characterizing this public health issue. This study aims to explore the prevalence, spatial distribution, and risk factors for CKD among patients receiving haemodialysis (HD) in the region. Methodology: A cross-sectional survey of HD centres in Yobe, Borno, and Jigawa States of Nigeria was conducted. Questionnaire responses were obtained on demographic, social, and clinical data. Spatial analyses were conducted to determine the geographic distribution of the cases. Results: We identified 376 patients receiving HD services across 4 centres. Of these, 207 (55.1%) were male and the mean age was 46.56 ± 16.4. Most patients reside in urban areas (67.6%). The main pre-dialysis occupations included civil service (100 [26.6%]), agriculture (65 [17.3%]), and trading (58 [15.4%]). 'Hypertension' (195 [51.9%]) was the most common self-reported primary renal disease, followed by unknown causes (70 [18.6%]) and Diabetic Kidney Disease (30 [8%]). Regional analysis demonstrated a particularly high burden of disease in Bade and Jakusko Local Government Areas. Conclusion: Spatial analysis suggests the existence of a CKD hotspot geographically associated with communities along the River Yobe, raising the possibility of an important environmental cause of disease. This study also highlights the lack of access to adequate diagnosis and geographical clustering of CKD burden in this region. These findings further reinforce the need for population-representative studies to characterize the burden of CKD alongside strategic healthcare interventions and collaboration among stakeholders aimed at improving access to care.xs.
Source: medRxiv
Authors: Baba Waru Goni, Baba Waru Goni, Hamidu Suleiman Kwairanga, Aliyu Abdu, Ibrahim Ummate, Alhaji Abdu, Ahmed Ibrahim Ba’aba, Mohammad Maina Sulaiman, Loskurima Umar, M.L Gana, Aliyu Abdulkadir, Sabiu Musa, Shatuwa Adamu, Idris A. Usman, Hauwa Alhaji Sabo, Idris Musa Abubakar, Hamza Bukar Adam, Ismail Alhaji Umar, Ayabaryu Papka, Modu Mustapha, Yauba Mohammed Saad, Amin Oomatia, Mahmoud Bukar Maina, Neil Pearce, Ben Caplin
Institutions: Yobe State University, University of Maiduguri, Gombe State University, Aminu Kano Teaching Hospital, Bayero University Kano, Federal University Dutse, African Field Epidemiology Network, Federal Medical Centre Nguru, University College London, London School of Hygiene & Tropical Medicine
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4412650180