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Chronic alcohol consumption induces phenotypic and functional alterations consistent with a hyper-inflammatory state in peripheral blood mononuclear cell-derived microglia in a rhesus macaque model

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Year: 2025
Type: article
Source: Brain Behavior and Immunity
DOI: 10.1016/j.bbi.2025.07.022
Authors: Hami Hemati, Madison B. Blanton, Heather E. True, Jude Koura, Rupak Khadka, Kathleen A. Grant, Ilhem Messaoudi
Institutions: University of Kentucky, Oregon National Primate Research Center, Oregon Health & Science University
Language: English

Topic: Neuroinflammation and Neurodegeneration Mechanisms
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Institute on Alcohol Abuse and Alcoholism, National Institute on Aging
Awards: Support for National Primate Research Center, Impact of chronic alcohol consumption on the functional and epigenetic landscapes of monocytes and their progenitors, 6/8: INIA Stress and Chronic Alcohol Interactions: Stress and Ethanol Self Administration in Monkeys, Monkey Alcohol Tissue Research Resource (MATRR), Uncovering the functional and mechanistic dysregulation of monocytes after abstinence and post-abstinence drinking
OpenAlex ID: W4412657345
FWCI: 0.361
Cites: 127
Cited by: 1
Related to: 10
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