Targeted nano-drug delivery systems for tumor immunotherapy
Year: 2025
Type: article
Abstract: While being a safe and effective precision therapy strategy, tumor immunotherapy still fails in many patients due to the immunosuppressive tumor microenvironment. Emerging evidence has indicated that the targeted nano-drug delivery systems can accurately deliver therapeutic agents to potentiate the efficacy of immunotherapy. This review will outline recent advances in applying targeted nano-drug delivery systems in immunotherapy, with an emphasis on their crucial roles in regulating innate immune responses, adaptive immune responses, and immunogenic cell death. We will also discuss the current challenges and future opportunities for the clinical translation of targeted nano-drug delivery systems for tumor immunotherapy.
Authors: Shan Lian, Wenyong Yang, Yan Zeng, Ranran Tang, Kui Wang
Institutions: Sichuan University, West China Medical Center of Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Third People's Hospital of Chengdu, First Affiliated Hospital of Xinxiang Medical University, Southwest Jiaotong University, Chongqing Medical University, Nanjing Medical University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,950
OpenAlex ID: W4412664655