Work

Optimization of pyrrole-2-carboxamide to develop a potent antituberculosis agent with improved physicochemical property and druggability

Year: 2025

Type: article

Source: Bioorganic Chemistry

DOI: 10.1016/j.bioorg.2025.109016

Authors: Yanan Wu, Hongyi Zhao, Bin Wang, Xi Chen, Bo Jin, Yixuan Zheng, Chen Ma, Li Sheng, Yu Lu, Haihong Huang, Dongfeng Zhang

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Chinese Materia Medica, Capital Medical University, Beijing Chest Hospital

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Chinese Academy of Medical Sciences

Awards: G4339664968, G6968012532, G7824872500, G8527685911

OpenAlex ID: W4414484352

FWCI: 2.312

Cites: 21

Cited by: 3

Related to: 10