Work

Targeting N6-methyladenosine demethylase FTO overcomes osimertinib resistance by inducing G0/G1 phase arrest in an m6A-dependent manner in lung adenocarcinoma

Year: 2025

Type: article

Source: Biochemical Pharmacology

DOI: 10.1016/j.bcp.2025.117198

Authors: Jun Chen, Chengru Hu, Jing Wu, Zhanwen Liang, Jing Qian, Chao Chen, Haitao Huang, Yong Zhu, Yun Zhao, Yan Li

Institutions: Soochow University, First Affiliated Hospital of Soochow University

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Jiangsu Commission of Health, National Natural Science Foundation of China, Priority Academic Program Development of Jiangsu Higher Education Institutions, Science and Technology Program of Suzhou

Awards: G2640801462, G2946179240, G5877003110, G7100051831

OpenAlex ID: W4412710622

FWCI: 0.651

Cites: 52

Cited by: 1

Related to: 10