Comparison of prognosis between intravascular ultrasound-guided and angiography-guided percutaneous coronary intervention in patients with acute coronary syndrome
Year: 2025
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To compare the prognosis of intravascular ultrasound (IVUS)-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). METHODS: This retrospective cohort study included 190 ACS patients who underwent PCI between January 2019 and January 2024. Patients were equally divided into two groups: IVUS-guided (n=95) and angiography-guided PCI (n=95). Baseline characteristics, procedural details, and clinical outcomes were analyzed. Follow-up duration was one year. Primary endpoints included cardiac function parameters, target vessel-related events, major adverse cardiovascular and cerebrovascular events , and quality of life (QoL) measures. RESULTS: The IVUS-guided group demonstrated better procedural outcomes, with significantly lower stent volume (P=0.002) and reduced neointima volume at 9 months (P=0.002). Improvements in cardiac function were more notable in the IVUS group, reflected in lower post-treatment left ventricular end-diastolic volume index (P=0.004) and end-systolic volume index (P=0.003). QoL scores were significantly higher in physical function (P=0.001) and social function (.002). However, IVUS-guided procedures required longer procedural time and greater contrast media use. CONCLUSION: IVUS-guided PCI yields superior procedural precision, improved cardiac function, and better quality of life compared to angiography-guided PCI in ACS patients, with acceptable trade-offs in procedural complexity.
DOI: 10.62347/gakw8223
Author: Shiming Zhao
Institution: Wuhan Hankou Hospital
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4412775462