Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: The most prevalent cause of hemolytic disorders of newborn (HDN) is ABO incompatibility.It occurs as a result of ABO blood group incompatibility between the mother and fetus.So, the aim of the present study was to assess the outcome of newborns with ABO incompatibility Aim of the study: The aim of this study was to evaluate the outcome of neonates with ABO incompatibility in a tertiary care hospital.Methods: This cross-sectional type of observational study was carried out on all icteric newborns admitted to Shaheed Suhrawardy Medical College Hospital during a 6-month period, from July 2013 to January 2014, in Dhaka, Bangladesh.Among forty-nine patients admitted with neonatal jaundice, ABO incompatibility was found in 30 cases.Cases were detected according to history, examination and fulfillment of criteria.Results: Among the ABO incompatibility cases, the age of onset of jaundice, noticed by parents were: 1st 24 hours, 11 (36.67%)cases, 24 hours to 72 hours, 16 (53.33%)cases and >72 hours, 5 (16.67%) cases.Coomb's test was negative in all the cases.Exchange transfusion was needed in 4 (13.33%)cases, 26 patients improved with phototherapy alone (86.67%) and the duration of phototherapy was >48 hours in 20 cases (66.67%) and ≤48 hours in 10 (33.33%) cases.Conclusion: Phototherapy is an effective measure in treating hyperbilirubinemia in most cases, and it reduces the need for exchange transfusions.But phototherapy should not be used as a substitute when there is an indication for an exchange transfusion.
Source: ARC Journal of Pediatrics
Language: English
Topic: Blood groups and transfusion
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412777843