Work

Neighborhood characteristics of expanded access patients at an academic referral center

Year: 2025

Type: article

Abstract: Expanded access (EA) is a United States regulatory approach for the use of investigational drugs/devices that do not yet have conventional approval, in clinical care contexts. We conducted a retrospective study to analyze the neighborhood characteristics of patients who have received EA treatments at our academic medical center between 2018 and 2023. EA patient neighborhoods showed lower median family income, lower proportion of bachelor's degree graduates, and a higher proportion of people identifying as non-Hispanic White ethnicity compared to the surrounding (Washtenaw) county. These differences may underly differential interest in EA treatments or may point to disparities in access to evidence-based care.

Source: Journal of Clinical and Translational Science

DOI: 10.1017/cts.2025.10115

Authors: Misty Gravelin, Jeanne Wright, Adrian Weyhing, Vikas Kotagal

Institutions: University of Michigan, VA Ann Arbor Healthcare System

Language: English

Topic: Ethics in Clinical Research

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDGs: Reduced inequalities, Good health and well-being

Open Access status: gold

Estimated APC paid: $3,200