Work

Candida glabrata chorioamnionitis following IVF pregnancy

Year: 2025

Type: article

Abstract: Fungal chorioamnionitis is a rare but potentially life-threatening complication of pregnancy with significant maternal and fetal consequences. We describe a severe case of Candida glabrata chorioamnionitis in a 19-week twin pregnancy conceived through in vitro fertilization (IVF), resulting in maternal septic shock and fetal demise. The patient was successfully treated with anidulafungin after the identification of C. glabrata in blood and placental cultures. This case highlights the growing association between assisted reproductive technologies and fungal chorioamnionitis, emphasizing the need for increased awareness, early diagnosis, and appropriate management of this condition. The literature review suggests a significant relationship between IVF procedures and C. glabrata infections, with implications for pre-procedural screening and prophylaxis in high-risk patients.

Source: IDCases

DOI: 10.1016/j.idcr.2025.e02325

Authors: Junais Koleri, Hani Ghassan Hamad, Fatma Ben Abid, Sreethish Sasi, Ajithkumar V. Ittaman, Muna AlMaslamani

Institution: Hamad Medical Corporation

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,370