Work

Cu 2 O-mediated regio- and stereoselective one-pot synthesis of ( Z )-3-ylidenephthalides from 2-iodobenzoic acids and terminal alkynes

Year: 2025

Type: article

Abstract: O in DMF at 100-130 °C. Our copper(I) oxide-catalyzed reaction requires no additional palladium, ligand, or base, making it an economical and efficient process. This optimized method is applicable to a range of 2-iodobenzoic acids and alkynes with diverse electronic, steric, and stability characteristics.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/d5ob00808e

Authors: Ahmed R. Ali, Longqin Hu

Institutions: Rutgers, The State University of New Jersey, Mansoura University, Rutgers Cancer Institute

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

OpenAlex ID: W4412789044

FWCI: 0.596

Cites: 84

Cited by: 2

Related to: 10