Managing pregnancy in a patient with Von Willebrand disease: a case report of tailored hemostatic care
Year: 2025
Type: article
Study design: Case Report
Abstract: A hemostatic condition known as Von Willebrand disease (VWD) is defined by a quantitative or qualitative deficit of the Von Willebrand factor (VWF). Both men and women are equally impacted. With a mean diagnostic age of 19 years old, this illness presents with more severe clinical signs in females of reproductive age. Von Willebrand disease increases the chance of postpartum hemorrhage and its associated complications from transfusion support and multiorgan injury from tissue hypoperfusion in pregnant patients. These factors increase the risk of complications during labor or the postpartum period. We describe the case of a 35-year-old primigravida woman who had Von Willebrand disease diagnosed before she became pregnant. While not administered, the institutional procedure for addressing this condition included obtaining and being ready for the administration of Von Willebrand factor and factor VIII (FVIII) throughout the postpartum period and caesarean birth. With an increase in Von Willebrand factor levels, this led to the successful management of prenatal and postpartum hemorrhage, preventing the need for blood transfusions and the subsequent hypoperfusion symptoms. The importance of specialist therapy for Von Willebrand disease during pregnancy and childbirth is shown by this instance, which also highlights the need of following institutional procedures, including certain hemostatic agents. For the thorough care of females with this illness throughout the perinatal period, the cooperative efforts of a multidisciplinary team, comprising obstetricians, hematologists and other medical specialists, are essential.
Source: Ginecologia ro
Author: Smit Bharat Solanki
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412809151