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Preparation and characterization of Low molecular weight chitosan by cellulase digestion

Year: 2025

Type: article

Abstract: Chitosan is up to present the only discovered cationic natural sugar. Moreover, small molecule chitosan is essentially valued as it is extraordinary suitable for fabrication of nanosize particle encapsulated medicine delivery system. Therefore, preparation of small-molecule chitosan has significant applications. 10% concentration cellulase to digest raw CS (Mw=1.5×105) resulting of 4.9×104 of LWCS, which are successively confirmed by FT-IR characterization, XRD analysis, DD testing and viscosity comparison. It verified enzyme digestion is an effective tool for LWCS preparation.

Source: Advances in Engineering Technology Research

DOI: 10.56028/aetr.14.1.209.2025

Authors: Qi Yin, Fang Yang, Xiaoling Lu, Xuehan Wu, Liya Chen, Lin Zhang, Kang Yang, Hao Li, Zeng Yang, You Long, Chao Shen, Bo Yao, Chenghong Huang

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: diamond

Funder: Chongqing University of Science and Technology

OpenAlex ID: W4412818911

FWCI:

Cites: 2

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Related to: 10