Work

Reversibility of FUS-aided blood–tumor barrier opening for the delivery of therapeutics

Year: 2025

Type: article

Abstract: In a dual-GBM mouse model, FUS was applied to selectively open the blood–tumor barrier in one tumor to assess 18 F-avelumab and 18 F-FDS penetration over 1–72 h, addressing whether FUS-induced barrier disruption is reversible.

Source: RSC Pharmaceutics

DOI: 10.1039/d5pm00088b

Authors: Céline Chevaleyre, Sophie Tran, Mylène Richard, Laurène Jourdain, Dimitri Kereselidze, Benoit Jego, Erwan Selingue, Benoit Larrat, Sébastien Mériaux, Nicolas Tournier, Anthony Novell, Charles Truillet

Institutions: Centre National de la Recherche Scientifique, Inserm, Commissariat à l'Énergie Atomique et aux Énergies Alternatives, CEA Paris-Saclay, Laboratoire d'Imagerie Biomédicale Multimodale Paris-Saclay, Université Paris-Saclay, Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields

Language: English

Topic: Ultrasound and Hyperthermia Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Institut National Du Cancer

Award: France Life Imaging

OpenAlex ID: W4412824020

FWCI:

Cites: 19

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Related to: 10