Work

Mild synthesis of fused polycyclic 1,6-naphthyridin-4-amines and their optical properties

Year: 2025

Type: article

Abstract: -mediated Friedel-Crafts-type intramolecular cycloaromatisation of 4-(arylamino)nicotinonitriles in which the cyano group acts as a one-carbon synthon. The transformation achieves good to excellent yields and can be performed on a gram scale. Additionally, the exploration of fluorescence properties of these compounds demonstrates their potential application as fluorophores.

Source: RSC Advances

DOI: 10.1039/d5ra03301b

Authors: Ze Li, Dongfeng Zhang, Hanxun Wang, Haihong Huang, Maosheng Cheng, Hongyi Zhao

Institutions: Shenyang Pharmaceutical University, Chinese Academy of Medical Sciences & Peking Union Medical College

Language: English

Topic: Synthesis of heterocyclic compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funders: National Natural Science Foundation of China, Chinese Academy of Medical Sciences