Work

Radical cascade cyclization of amino acid-tethered 1,6-enynones with sulfonyl hydrazides for N-terminal modification: synthesis of functionalized succinimide derivatives

Year: 2025

Type: article

Abstract: ratio, moderate to good yields, and was synthesized on a gram-scale. Furthermore, the synthetic utility of the product 5aa was performed by (i) Suzuki coupling reaction with iodo-functionality; and (ii) dipeptide formation using glycine methyl ester.

Source: RSC Advances

DOI: 10.1039/d5ra04754d

Authors: Mathiyazhagan Sivanantham, Jenis Jacob Stanley, Kesavan Muthu, Sivan Velmathi, Gopal Chandru Senadi, Mohankumar Ramasamy

Institutions: SRM Institute of Science and Technology, National Institute of Technology Tiruchirappalli

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funders: SRM Institute of Science and Technology, VIT University