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Ketamine-Assisted Psychotherapy for Addiction: Mechanisms, Evidence, and Clinical Implications

Year: 2025
Type: article
Abstract: Substance use disorders (SUDs) are notoriously difficult to treat due to complex biopsychosocial underpinnings and high relapse rates. Recent evidence positions ketamine-assisted psychotherapy (KAP) as a promising intervention for treatment-resistant addiction. This review explores ketamine’s neurobiological mechanisms, its synergistic effect with psychotherapy, and clinical data supporting its efficacy in various substance use disorders. Additionally, it addresses safety concerns and outlines practical considerations for integration into clinical practice.
Authors: Allay Health and Wellness in Palm Beach Gardens,FL, USA., Ryan Ward
Language: English
Subfield: Pharmacology
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W4412849152
FWCI:
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