Automated Hypothermic Machine Perfusion for Donor Kidney Preservation
Year: 2025
Type: article
Abstract: Purpose: Historically, hypothermic machine perfusion (HMP) devices operate based on a user-defined pressure, where flow is influenced by renal vascular resistance (RVR) and perfusion pressure. As a result, for any given RVR, flow can vary depending on the user -defined pressure, limiting the reliability of flow as an objective metric for assessing kidney performance. Here, we introduce a novel HMP device that automatically adjusts flow in response to the intrinsic RVR of the kidney, leveraging a flow regulator valve to control perfusion parameters.
Authors: S. Estrella, M. Tajima, M. Devlin, J. Miles, P. Patel, M. Whitney, D. Macari, L. Churchill
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4412850590