Work

Delayed-Graft Function and Fate of Transplant Survival Assessment: The Promotor Region of Cytokine Genes

Year: 2025

Type: article

Abstract: Purpose: Delayed graft function (DGF)is a common index of kidney injury during the process and outcome of long- time survival of kidney transplant. Thus, the ability to predict DGF is important in determination of the cold ischemia time (CIT) and the treatment strategies. Genomic polymorphisms within the promotor region of the cytokines have been suggested to influence the outcome of allograft function. IL-18, IFN-γ, and IL-10 are cytokines associated with the recipient’s immune response genes, affecting the outcome of allograft survival.

Source: American Journal of Transplantation

DOI: 10.1016/j.ajt.2025.07.1265

Authors: D.O. McDaniel, F.K. Butt, L.S. McDaniel, A.M. Hawxby

Institutions: University of Mississippi Medical Center, Pennsylvania State University, Penn State Milton S. Hershey Medical Center

Language: English

Topic: Renal Transplantation Outcomes and Treatments

Subfield: Transplantation

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,300