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Impact of Active Hepatitis C Virus Infection on Post-Liver Transplantation Outcomes in the Direct-Acting Antiviral Era

Year: 2025

Type: article

Abstract: Purpose: Following introduction of Direct-acting antivirals (DAAs) for HCV treatment, most patients achieve sustained viral response (SVR); however, optimal timing for HCV treatment in patients listed for liver transplantation (LT) remains debated. This study analyzes the OPTN dataset to assess the impact of HCV status on post-LT outcomes to determine whether active HCV infection at LT impacts post-op complication following LT.

Source: American Journal of Transplantation

DOI: 10.1016/j.ajt.2025.07.749

Authors: Y. Shah, G.G. Panayotova, T. Reno, S. Simonishvili, Y. Qin, T. Zoumpou, L. Jin, T. Ayorinde, A. Xynogala, J. Medina-Morales, S. Alimdjanova, C. Pierre, F. Paterno, A. Amin, G. Lee-Riddle, P. Gaglio, J. Guarrera, K. Lunsford

Language: English

Topic: Hepatitis C virus research

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,300

OpenAlex ID: W4412852013

FWCI:

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