Changes in Immune Cell Markers: A Cross-Sectional Analysis of the Elderly Wait-Listed and Kidney Transplant Recipients
Year: 2025
Type: article
Study design: Observational Study
Abstract: Purpose: Infections, cardiovascular disease, and malignancy are the leading causes of mortality in elderly kidney transplant recipients (KTRs). While acute rejection is less frequent in elderly KTRs, immunosenescence may lead to infections and cancer . The aim of this study is to assess changes in immune markers of senescence, regulation, metabolism, and mitochondrial function in the elderly KTRs versus elderly wait-listed (WL) patients and correlate them with clinical metrics, including the six-minute walk test, infections, and rejection episodes.
Authors: L. Kodali, A.N. Ligezka, N. Zhang, P. Zamani, T.M. Johnston, G. Mour, M. Khosravi Maharlooei
Institutions: Mayo Clinic in Arizona, Mayo Clinic Hospital, Mayo Clinic
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4412852169