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Randomized Clinical Trial of SARS-CoV-2 Peri-Vaccination Immunosuppressive Reduction in Kidney and Liver Transplant Recipients

Year: 2025
Type: article
Abstract: Purpose: Solid organ transplant recipients (SOTRs) demonstrate weak antibody (Ab) response to SARS-CoV-2 vaccines despite repeated boosting. Immunosuppressive reduction (ISR) might improve responses, yet safety and immunogenicity are not established.
DOI: 10.1016/j.ajt.2025.07.609
Authors: W. Werbel, Z. Nauroz, A. Karaba, D. Brown, N. Watson, B. Barnaba, S. Aslam, M. Fung, S. Borgetti, E. Blumberg, M. Rana, S. Pouch, J. Garonzik Wang, W. Clarke, C. Small, M. Bettinotti, S. Hamrah, L. Li, A. Tobian, A. Massie, C. Larsen, P. Heeger, D. Segev, C. Durand
Institutions: Johns Hopkins University, National Institutes of Health, University of California San Diego, University of California, San Francisco, University of Illinois Chicago, Cornell University, New York University
Language: English
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4412852381
FWCI:
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