Prospective Eplet Matching in Unsensitized Recipients of Living Donor Kidneys is Associated with a Lower Incidence of De Novo DSA
Year: 2025
Type: article
Study design: Observational Study
Abstract: Purpose: Human leukocyte antigen (HLA) eplet matching has been shown to reduce de novo donor specific antibody (dnDSA) production independent of HLA antigen matching in retrospective studies. We describe outcomes after living donor kidney transplantation (LDKT) with prospective evaluation of donor-recipient eplet matching via a national paired exchange program.
Authors: R. Kandaswamy, A. Matar, N. Ali, A. Leonberg-Yoo, D. Morris, M. Prieto, S. Tullius, S. Kapur, M. Cooper, J. Verbesey, G. Morgan, D. Mandelbrot, C. Jadlowiec, C. Klein, D. Maurer, M. Mangiola, A. Thomas, A. Massie, D. Segev, M. Ronin, G. Hil, R. Montgomery
Institutions: University of Minnesota, New York University, University of Pennsylvania, Intermountain Healthcare, Mayo Clinic, Brigham and Women's Hospital, Weill Cornell Medical Center, Medical College of Wisconsin, Georgetown University Medical Center, Hartford Hospital, University of Wisconsin Health, Mayo Clinic in Arizona
Language: English
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W4412852584