Work

Dobutamine Stress Echocardiography for Left Ventricular Reverse Remodeling in Idiopathic Dilated Cardiomyopathy

Year: 2025

Type: article

Abstract: Background and Objectives: Left ventricular reverse remodeling (LVRR) reflects a good prognosis in patients with idiopathic dilated cardiomyopathy (IDCM). This study aimed to evaluate the usefulness of contractile reserve on dobutamine stress echocardiography (CR-DSE) for predicting LVRR in patients with IDCM. Methods: A total of 38 patients with IDCM were enrolled between March 2014 and May 2018. All patients underwent echocardiography and cardiac magnetic resonance imaging at baseline, and echocardiography at 6 months. Results: Among 38 patients, 22 (57.9%) exhibited CR-DSE at baseline, and 14 (36.8%) experienced LVRR at 6 months. LVRR occurred in 12 of the 22 patients with CR-DSE (54.5%) and in 2 of 16 patients without CR-DSE (12.5%) (p<0.05). In multivariate logistic regression analysis, a CR-DSE was an independent predictor of LVRR (odds ratio, 1.24; 95% confidence interval, 1.01-1.51; p=0.043). Delta LV ejection fraction during DSE also predicted LVRR (area under the curve: 0.765; p=0.007). Conclusions: Preserved CR-DSE was significantly associated with LVRR at 6 months, suggesting its potential utility as a functional predictor of myocardial recovery in patients with IDCM.

Source: International Journal of Heart Failure

DOI: 10.36628/ijhf.2024.0071

Authors: Hyun-Min Choi, Jung-Woo Son, Se-Eun Kim, Jang Young Kim, Byung Su Yoo

Institutions: Yonsei University, Wonju Severance Christian Hospital

Language: English

Topic: Cardiovascular Function and Risk Factors

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412861244