Work

Impact of Absolute Lymphocyte Count-Guided Surveillance on Early Detection of Cytomegalovirus After Prophylaxis in High-Risk Kidney Transplant Recipients

Year: 2025

Type: article

Abstract: Purpose: CMV infection after prophylaxis remains a major cause of morbidity in high-risk (D+/R-) kidney transplant recipients. Low absolute lymphocyte counts have been associated with increased risks of CMV infection. We evaluated whether a surveillance protocol based on absolute lymphocyte count (ALC) could enable earlier detection and improve clinical outcomes at 1-year post-transplant.

Source: American Journal of Transplantation

DOI: 10.1016/j.ajt.2025.07.1374

Authors: C. A. Portales Castillo, A.G. Stewart, L.V. Riella, C.N. Kotton

Institution: Massachusetts General Hospital

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,300