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Nanocarriers in Targeted Drug Delivery: Design Strategies to Overcome Biological Barriers

Year: 2025
Type: article
Abstract: Effective drug delivery requires overcoming multiple biological barriers, including enzymatic degradation, immune clearance, and poor tissue penetration. This review systematically presents the design strategies for nanocarriers — including surface modification, stimuli-responsive release, and active targeting ligands — to enhance therapeutic index and specificity. We discuss recent advances in polymeric nanoparticles, liposomes, dendrimers, and exosome-based carriers, emphasizing their applications in cancer, infectious diseases, and neurological disorders
Language: English
Subfield: Biomaterials
Open Access status: hybrid
OpenAlex ID: W4412878478
FWCI: 0.557
Cites:
Cited by: 3
Related to: 10