Research Progress of Traditional Chinese Medicine in the Treatment of Interstitial Pulmonary Fibrosis Disease
Year: 2025
Type: article
Abstract: 间质性肺纤维化(Interstitial Pulmonary Fibrosis, IPF)是一种发生在肺部的以弥漫性肺泡炎症、细胞结构紊乱及间质纤维化为特征的慢性、进展性、不可逆的间质性疾病。然而现代医学治疗肺纤维化的手段十分有限，近些年来中医药在改善肺纤维化疾病的临床症状、延缓纤维化进展等方面展现出独特优势，研究显示，中药复方或中医艾灸联合西药(吡非尼酮、尼达尼布)可显著改善患者肺功能，延缓纤维化的进展，且具有良好的安全性。本文结合了近年来国内外关于中医药治疗间质性肺纤维化疾病的研究，探讨从中医病名归属、中医药治疗间质性肺纤维化的理论基础、作用机制及临床疗效的研究进展，以期可以为IPF的治疗提供新的思路和方向。Interstitial pulmonary fibrosis (IPF) is a chronic, progressive and irreversible interstitial lung disease characterized by diffuse alveolar inflammation, cellular structural disorder and interstitial fibrosis. However, modern medical treatment options for pulmonary fibrosis are quite limited. In recent years, traditional Chinese medicine has demonstrated unique advantages in improving clinical symptoms of pulmonary fibrosis and delaying the progression of fibrosis. Studies have shown that traditional Chinese medicine formulas or the combination of traditional Chinese medicine moxibustion and Western medicine (pirfenidone, nintedanib) can significantly improve lung function in patients, delay the progression of fibrosis, and have good safety. This article combines domestic and international research on the treatment of interstitial pulmonary fibrosis with traditional Chinese medicine in recent years, and explores the research progress in the classification of traditional Chinese medicine disease names, theoretical basis, mechanism of action and clinical efficacy of traditional Chinese medicine in the treatment of interstitial pulmonary fibrosis, with the aim of providing new ideas and directions for the treatment of IPF.
Source: Advances in Clinical Medicine
Author: 兆云 刘
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4412884841