A Unique Finding in an Adolescent Male: A Case Report Navigating in Detail about Oral Neurofibroma
Year: 2025
Type: article
Study design: Case Report
Abstract: lymphadenopathy were observed.Provisional diagnoses given included pyogenic granuloma, lipoma, and traumatic fibroma. InvestIgatIonsAn incisional biopsy was planned under local anesthesia.2% lidocaine with 1:200,000 adrenaline was administered at the surgical site through local infiltration.The lesion was excised in toto using an elliptical incision.The lesion was dissected out from the underlying buccinator muscle.The wound was closed using 3-0 silk sutures.The excised lesion was sent for histopathological analysis.Macroscopically, the excised specimen appeared as an oval, well-defined soft tissue mass measuring 0.7 × 0.5 cm, grayish-brown in color, and was soft to firm in consistency. IntroductIonNerves are essential components of the human body's intricate communication system.Peripheral nerves are composed of bundles of nerve fibers, including both sensory and motor neurons.There can be various disorders that can arise from the peripheral nervous system (PNS) such that it can manifest as reactive lesions and benign and malignant conditions.[1][2][3] Seldom occurring soft tissue neoplasms are oral and maxillofacial tumors of neural origin.One such lesion is neurofibroma (NF), an uncommon type of tumor that originates from the cells of the peripheral nervous system, specifically the cells called Schwann cells, which produce the protective covering (myelin) around nerve fibers.They account for 29% of the neural lesions in the oral cavity and can present as a solitary lesion or as a component of the generalized neurofibromatosis syndrome, which is typically neurofibromatosis type 1 [NF-1], commonly known as von Recklinghausen disease of the skin.4,5 Clinically, oral neurofibromas typically manifest as slowgrowing sessile or pedunculated nodules.The tongue, buccal mucosa, alveolar ridge, labial mucosa, palate, gingiva, and alveolar ridge are common locations for solitary oral NF. 5,6 Oral NF is quite uncommon in nonsyndromic patients, and it is typically linked to NF-1.7 Through histologic inspection and immunohistochemistry, the diagnosis is verified.We report a case of neurofibroma arising from the buccal mucosa in a nonsyndromic adolescent male patient. case PresentatIonA healthy 17-year-old male patient reported with a complaint of a growth in the left buccal mucosa that had existed for 5 years.There was no association with pain or any habits.Intraoral examination revealed evidence of a sessile growth on the left buccal mucosa of size 0.5 × 0.5 cm (Fig. 1).The lesion was soft, nonulcerated, with normal color, and no sign of discharge was noted.The surrounding area appeared normal.
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412915667