Comparative Evaluation of the Effect on Enamel Solubility and Remineralizing Potential Following Surface Treatment with Fluoride-alone Varnish and Two Fluoride Varnishes Containing Calcium and Phosphate Additives: An In Vitro Study
Year: 2025
Type: article
Abstract: calcium phosphate, 3 has been previously studied in comparison to traditional topical fluoride Varnishes, a thorough review of both print and electronic sources found limited research evaluating the impact of MI Varnish and Embrace Varnish on enamel solubility.8 One study has investigated the remineralization ability of these two Varnishes.3 In view of the paucity of evidence, the present study was conducted to assess and compare the remineralizing potential and effect on enamel solubility of conventional topical fluoride IntroductIonNumerous strategies have been utilized to preserve the structural integrity of enamel.The application of fluoride in various forms is a well-established approach that strengthens the enamel structure by forming stronger fluorapatite crystals, thereby increasing resistance to demineralization. 1 Topically applied fluoride Varnishes are professionally applied adherent materials that consist of a high concentration of fluoride as a salt or saline preparation in a fast-drying, alcohol or resin-based solution.2 The caries-preventive effect of topical fluoride therapy depends on an adequate supply of calcium and phosphate ions.3 To increase the amount of calcium and phosphate in saliva and to further improve remineralization efficacy, fluoride Varnishes with added calcium and phosphate have been introduced recently.4 Several fluoride Varnish formulations incorporate calcium and phosphate in various forms, including functionalized tricalcium phosphate (fTCP), amorphous calcium phosphate (ACP), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), and xylitol-coated calcium and phosphate (CXP).These additions enhance mineral adherence to the tooth surface, reduce demineralization, promote remineralization, stabilize fluoride-calcium-phosphate ion phases, and help prevent the formation of unstable phases during storage.4,5 Although the anticaries effectiveness of fluoride Varnishes supplemented with calcium and phosphate, 1,[5][6][7] as well as those with xylitol-coated 1,
Authors: Sanketh K Karanth, Jaya Naidu
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
Funder: Ramaiah Institute Of Technology
OpenAlex ID: W4412915883