Work

Prevention of glucose toxicity after cornelian cherry and bee bread treatment in spontaneous animal model of diabetes

Year: 2025

Type: article

Abstract: Diabetes mellitus type 2 is a complex metabolic disease characterized by persistent hyperglycaemia. And it is chronic glucose toxicity that influences the development of other critical symptoms of diabetes mellitus. To prevent the occurrence and subsequent treatment of diabetes, new alternative sources are being sought. In our study, we focused on the effect of bee bread and cornelian cherry fruit (Cornus mas L.) administered jointly in a homogenized dose (500 mg.kg-1 each) by gastric tube on the onset and development of diabetes mellitus, on the alleviation of symptoms of glucose toxicity and insulin resistance. We found that regular consumption of these substances resulted in improved glycaemia and had a preventive effect on glucose toxicity in young rats suffering from DM2T. Further studies are required.

Source: Archives of Ecotoxicology

DOI: 10.36547/ae.2025.7.2.48-52

Authors: Patrícia Simkova, Anna Kalafova, Monika Schneidgenova, Klaudia Jaszcza, Hana Greifova, Marcela Capcarova

Institutions: Slovak University of Agriculture in Nitra, University of Agriculture in Krakow

Language: English

Topic: Natural Antidiabetic Agents Studies

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: diamond

OpenAlex ID: W4412917807

FWCI:

Cites:

Cited by:

Related to: 10