Work

Assessment of Bacterial Uropathogens and their Antibiotic Susceptibility in Rural Healthcare Facilities, Jamalpur, Bangladesh

Year: 2025

Type: article

Abstract: Urinary tract infections (UTIs) are common in Bangladesh and increasingly complicated by antibiotic resistance. This study aimed to identify uropathogens and their antibiotic susceptibility patterns in patients at a tertiary care center in Jamalpur. A six-month cross-sectional study analyzed 282 urine samples from suspected UTI cases. Bacterial identification followed standard microbiological methods, and antibiotic sensitivity was determined using the Kirby-Bauer disk diffusion method per CLSI guidelines. Out of 282 urine samples, 54 (19.1%) showed significant bacterial growth, while 228 (80.9%) had no significant growth. Gram-negative bacteria comprised 83.4% of the isolates, with Escherichia coli (66.7%) being the most prevalent, followed by Klebsiella spp. (11.1%), Pseudomonas spp., (3.7%), and Acinetobacter spp. (1.9%). Among Gram-positive organisms, Enterococcus faecalis (9.3%) and Staphylococcus aureus (5.6%) were predominant. Females accounted for 74.1% of positive cases, with the highest prevalence in patients over 49 years of age. High resistance was observed to commonly used antibiotics such as ceftriaxone (81.5%) and chloramphenicol (94.4%), whereas meropenem (96.3%) and netilmicin (85.2%) showed the highest sensitivity.

Source: INTERNATIONAL JOURNAL OF HEALTH & MEDICAL RESEARCH

DOI: 10.58806/ijhmr.2025.v4i7n05