Year: 2025
Type: article
Study design: Case Report
Abstract: Myasthenia gravis (MG) is an autoimmune disorder in which antibodies block the acetylcholine receptors in the post synaptic membrane causing skeletal muscle weakness. The weakness can be localized or diffuse. MG predominantly affects the bulbar muscles and 15% of the cases are confined to the ocular muscles. Although MG is classically recognized as a disorder of muscle function, non-motor manifestations, particularly altered somatic sensation, are overlooked and underreported. This under recognition has contributed to a limited awareness among clinicians regarding the wider range of MG presentations. MG is a disease that can manifest with both motor and sensory symptoms. We present the case of a male patient subsequently diagnosed with thymoma, who initially exhibited abnormal sensory perceptions prior to the onset of muscular weakness. The diagnosis of MG was only established following the development of motor impairment. This case underscores the need for heightened clinical suspicion regarding atypical presentations of MG. The underappreciation of sensory symptoms may delay diagnosis and contribute to increased patient morbidity.
Institution: King's College Hospital
Language: English
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4412919917