Year: 2025
Type: article
Study design: Case Report
Abstract: BACKGROUND: Candida auris ventriculitis is a rare but serious condition associated with high mortality rates. The available literature on its management is limited, and there are few documented successful treatment strategies or care plans. CASE PRESENTATION: We report the case of a 34-year-old male patient from South Asia with Candida auris infection of an external ventricular shunt. The patient was initially treated with a combination of injectable amphotericin B liposomal and caspofungin for 21 days. This was followed by a 15-day course of injectable amphotericin liposomal and voriconazole. Subsequently, voriconazole monotherapy was administered orally for an additional 11 days. Notably, all antifungals used were determined to be sensitive on the basis of cerebrospinal fluid culture and sensitivity results. Source control was achieved after 20 days of initiating therapy, leading to the permanent removal of the shunt. CONCLUSION: Candida auris ventriculitis can be effectively managed with systemic antifungal therapy and appropriate source control measures.
Source: Journal of Medical Case Reports
Authors: Ahmad Elhaj, Duaa Jawhar, Nawal Elfaki
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,890
OpenAlex ID: W4412956532