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The relationship between lipids level and cerebral microbleeds in patients with spontaneous intracerebral hemorrhage.

Year: 2025

Type: article

Abstract: Background: Previous studies indicate a potential link between elevated serum lipid levels and an increased risk of cerebral microbleeds (CMBs). Since multiple CMBs can elevate the risk of future intracerebral hemorrhage (ICH), it is important to explore the relationship between lipid profiles and CMBs in ICH patients. However, data on this specific correlation in ICH populations are currently limited. Methods: This study retrospectively enrolled 223 consecutive patients from a spontaneous ICH cohort. We collected comprehensive clinical, demographic, and laboratory data, with a focus on lipid levels and the presence of CMBs. Using a multivariate logistic regression model, we investigated the association between lipid parameters and CMB occurrence. Results: = 0.043) were identified as independent predictors of lobar CMBs. Conclusion: Our findings suggest an inverse correlation between TC and Non-HDL levels and the presence of lobar CMBs in ICH patients. Further prospective studies are needed to clarify the causal relationship between statin use and CMBs in ICH patients and to evaluate the prognostic significance of CMB presence and severity in statin-treated individuals.

Source: PubMed

DOI: 10.3389/fneur.2025.1619440

Authors: Hao Feng, Xin Wang, Wenjuan Wang, Xingquan Zhao

Institutions: Capital Medical University, Beijing Tian Tan Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Institute for Brain Disorders

Language: English

Topic: Intracerebral and Subarachnoid Hemorrhage Research

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4412957809

FWCI:

Cites: 23

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Related to: 10