Work

Electrochemical investigation of paracetamol at Congo red modified carbon paste electrode: a voltammetric study

Year: 2025

Type: article

Abstract: This work illustrates the modification of carbon paste electrode (CPE) by electropolymerization of Congo red. The poly(Congo red) modified CPE (Congo red/MCPE) was used to study the electrochemical behaviour of paracetamol (PA) by cyclic voltammetry. Compared to bare CPE, Congo red/MCPE exhibited better electrocatalytic activity towards the oxidation of PA, with an enhanced oxidation peak current in phosphate buffer solution at neutral pH and a sweep rate of 100 mV s-1. The effect of analyte concentration changes at Congo red/MCPE was studied by varying the concentration of PA and the limit of detection was found to be 1.1 µM. The proposed approach was successfully applied to the simultaneous measurement of paracetamol and dopamine, with the modified electrode exhibiting relatively high sensitivity, selectivity, and stability. The applicability of the developed method to determine the drug in pharmaceutical samples (tablets) is also illustrated.

Source: Journal of Electrochemical Science and Engineering

DOI: 10.5599/jese.2640

Authors: Chethan Kuskur, Bahaddurghatta Eshwaraswamy Kumara Swamy

Institution: Kuvempu University

Language: English

Topic: Electrochemical sensors and biosensors

Subfield: Electrical and Electronic Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412962256

FWCI:

Cites: 50

Cited by:

Related to: 10