Hyperbaric Oxygen Therapy for Scleroderma Wounds: A Report on Two Cases and Literature Review
Year: 2025
Type: article
Abstract: Systemic sclerosis-associated wounds are often refractory to conventional wound care and pharmacotherapy. Hyperbaric oxygen (HBO2) therapy has a longstanding, yet infrequently documented, history of success healing wounds in patients with systemic sclerosis. Here, we present 2 cases of scleroderma-associated cutaneous wounds, unresponsive to standard treatments, successfully treated with HBO2. Additionally, we reviewed the current literature for articles that used HBO2 adjunctively with wound care in systemic sclerosis. These published studies showed an overall success rate of 81%.
Authors: Chih Yu Fang, Kevin D. Kerin, Jay C. Buckey
Institutions: Dartmouth–Hitchcock Medical Center, Dartmouth College
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412983028
