Metastatic Pancreatic Adenocarcinoma Manifesting as Otomastoiditis and Collet–Sicard Syndrome
Year: 2025
Type: article
Study design: Case Report
Abstract: Otomastoiditis is not prevalent in immunocompetent adults and in some cases can be caused by insidious malignancies of the temporal bone. Collet–Sicard syndrome (CSS) is a constellation of symptoms associated with unilateral lower cranial nerve deficits that can occur in the setting of radiologically elusive temporal bone malignancies. We present a rare case of an adult man with temporal bone biopsy–confirmed pancreatic cancer that initially presented with otomastoiditis and CSS. This case demonstrates how malignancy should remain a top differential diagnosis for clinicians who encounter immunocompetent adults with otomastoiditis, even when unsupported by advanced imaging modalities.
Authors: Alexander Herbert, Ji-Suk Moon, Aaron Domack, Alexander Velazquez, David Ward, Martin Manuel Cearras
Institutions: AdventHealth Orlando, AdventHealth
Language: English
Topic: Ear and Head Tumors
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412983042