Work

Azide-based difunctionalization of alkenes

Year: 2025

Type: article

Abstract: As an important class of nitrogen-containing functional molecules, azides have attracted considerable attention in synthetic chemistry and functional materials due to their reaction diversity and derivatization capability. Azide-based difunctionalization of alkenes, as a pivotal research direction in this field, holds significant implications for expanding the application scope of azide compounds through research progress and mechanistic innovations. This review focuses on reaction mechanisms to systematically summarize recent advances in azide-based difunctionalization of alkenes, while outlining its application prospects in synthetic methodology and interdisciplinary fields.

Source: Green Synthesis and Catalysis

DOI: 10.1016/j.gresc.2025.07.007

Authors: Minglin Tao, Haitao Tang, Yingming Pan

Institutions: Guangxi Normal University, Guilin Medical University

Language: English

Topic: Click Chemistry and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Innovative Research Group Project of the National Natural Science Foundation of China, National Natural Science Foundation of China, Specific Research Project of Guangxi for Research Bases and Talents

Awards: G451011477, G5571089082